This multidisciplinary course gives students the opportunity to understand the area of translational medicine and follow the development of a medical intervention from its basic scientific origins through public use . Given the relevance of the human papillomavirus vaccine to young people, this course investigates the human papilloma virus vaccine (HPV "Guardasil" vaccine) from disease through vaccine implementation.
Along the translational medicine path, students explore and discuss:
- science of the HPV disease
- animal models for intervention
- early translation to humans
- large-scale clinical trials
- initial introduction and marketing
- consideration of the problems of integration into routine practice
- late discovery of adverse effects
- cultural and economic barrier to diffusion
Students have the opportunity to analyze the clinical trial data and explore divergent views about the use of the HPV Guardasil vaccine.
This class is not a lab-based course, rather it is a course in which extensive discussion and debate occur.
The Ti2 team engages area research institutions and industries to help students understand how and why people are investigating the science behind and developing innovative solutions to the topics and issues covered in this course.
Over the course of the year, learning entry points may include the use of fiction and non-fiction literature, field trips, and art.